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Topic: Unit Operations

Pharma Sustainability Is on a Roll
Drug industry environmental stewardship projects are becoming more sophisticated and challenging. Here are examples from AstraZeneca, Bayer, DSM, Pfizer, and EMD Millipore

EMD Millipore: Giving and Receiving Single-Use Systems
A talk with sustainability manager Johanna Jobin about the company's new product recycling initiative.

Sartorius and G-Con: Bioprocess Cleanrooms Go Mobile
A joint collaboration claims it has a “disruptive technology” that can be shipped anywhere, and used in any way. Does it raise the bar for future flexible facilities?

Implementing Disposable Cleanroom Apparel into the Manufacturing Process
In the case of disposable cleanroom apparel the benefits can include an easier gowning process, elimination of variability in filtration performance that can result from reusing apparel, less waste and improved levels of contamination control.

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White Papers: In Depth Research

Examining the Role of TOC Analyzers in the Pharmaceutical Laboratory
Author: Shimadzu Scientific Instruments
Posted: 05/16/2012
Total Organic Carbon (TOC) analyzers serve a vital role in the pharmaceutical lab, in both the drug development and manufacturing processes. Presented here is an overview, as well as application examples showcasing TOC for Cleaning Validation and to address such guidelines as USP <643>.

The Safest Way to Calibrate: An Introduction to Intrinsically Safe Calibration
Author: Beamex
Posted: 02/07/2011
Intrinsically safe calibrators are not only the safest possible calibration equipment—used even for Zone 0 environments—but also provide the functionality and performance of regular industrial calibration devices. This paper provides a primer on the meaning and benefits of intrinsically safe calibration, as well as details on Beamex multifunction calibrators.

Turning Data Into Information: Making Sense of an Avalanche of Supply Chain and Production Data
Author: Bio-G
Posted: 01/28/2011
Biomanufacturing and operations research experts describe how to deal with staggering volumes of production and supply chain data. Learn how to convert this data into actionable information, which will be of value to the whole organization. Read about consolidating data from disparate sources, paramaterizing and visualizing data, building models for analysis and better decision making and a "complete systems" based approach to data consolidation, visualization and analysis.

Zeta Plus Activated Carbon Cartridges Evaluation & Scale-Up for Pharmaceutical Applications
Author: 3M Purification Inc.
Posted: 05/17/2010
This Technical Brief describes how the Zeta Plus Activated Carbon Cartridge series is evaluated for use in pharmaceutical applications and how the optimal carbon type and media grade are chosen for a given application. In addition, the brief describes how a process is scaled-up in order to determine the requisite Zeta Plus Activated Carbon filter area for manufacturing and production of an active pharmaceutical ingredient.

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